General Cell Lines and Cell Cultures
ATCC 2A3; Pharyngeal Carcinoma; Human (Homo sapiens)
2A3 is a cell line exhibiting epithelial-like morphology isolated in 2010 from the pharynx of a 56-year-old, White male with squamous cell carcinoma. It has applications for cancer research.
ATCC Escherichia coli; Strain P68
Escherichia coli strain P68 is a whole-genome sequenced bacterium that was isolated from cattle hides. This strain is non-toxigenic and is recommended by the USDA as a surrogate indicator organism to measure changes in microbial counts.
Eurofins Discoverx cAMP Hunter CHO-K1 PROKR1 Gs Cell Line, 2 vials. (95-0090C2)
The cAMP Hunter PROKR1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prokinectin, EG-VEGF) based activation of PROKR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type PROKR1, a naturally Gs coupled GPCR. Upon activation of PROKR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Discovery Life Sciences CRC Tx Naive PBMC
PBMCs Peripheral Blood Mononuclear Cells are immune cells isolated from whole blood and viably cryopreserved providing a foundational material for immunology studies cell therapy research and functional immune assays
ATCC Pseudomonas aeruginosa; Strain PGO2364
Pseudomonas aeruginosa strain PGO2364 is a bacterial strain that was isolated from the sputum sample of a cystic fibrosis patient during a Phase III clinical trial that tested the effectiveness of aerosolized Tobi (Tobramycin). The presence of a phage has been observed in this strain.
ATCC Escherichia coli; serovar O157:H7; Strain: ECP17-1298
For-profit Organizations: For every order of this item, you must work directly with the Centers of Disease Control to (i) negotiate a research-use license, and/or (ii) have the Centers of Disease Control provide authorization to ATCC to ship this item under your existing license. We cannot ship this item until we receive communication directly from the Centers of Disease Control that we are authorized to ship each order. We are providing the following contact information, but this information may change without notice: Centers for Disease Control, Technology Transfer Office, 1600 Clifton Road Atlanta, GA 30329-4027 Email: tto@cdc.gov. Once ATCC has received authorization from the Centers of Disease Control, your order will be reviewed, and this item will be released for shipment if all requirements are met. If you need assistance with your order, please contact our Customer Care team.
Eurofins Discoverx ChemiScreen M2 Muscarinic Acetylcholine Receptor Stable Cell Line, 2 vials. (HTS115C)
The ChemiScreen M2 Muscarinic Acetylcholine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. acetylcholine) based activation of CHRM2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Clostridioides difficile; Strain 630; Quantitative DNA
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load and for other molecular biology applications.
Eurofins Discoverx ChemiBrite EP2 Prostanoid Receptor Stable Cell Line, 2 vials. (HTS185L)
The ChemiBrite EP2 Prostanoid Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin E2) based activation of PTGER2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGER2 alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of PTGER2, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Staphylococcus aureus; 6 x 0.3mL
ATCC 43300-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 43300™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Sciencell Research Laboratories HUMAN HEPATIC SINUSOIDAL ENDOT
Human Hepatic Sinusoidal Endothelial Cells 5 x 10^5 cells/vial
